Karyopharm Therapeutics — 55 certified H-1B filings (FY2017–FY2026)

6
Filings · FY2025
$133k
Median base · FY2025
Clinical Data Manager
Top role · 4 all-time
MA
Top state · 46 all-time
FY

Karyopharm Therapeutics filed 6 certified H-1B LCAs in FY2025 (up 500% from the year before), with a median base salary of $133k and the middle 50% of offers between $124k and $140k. That is 14% above the market median for the same job titles. Across all years it has 55 certified filings since FY2017, most often for Clinical Data Manager in Massachusetts.

How much does Karyopharm Therapeutics pay H-1B workers?

Certified base salary by fiscal year: each box is the p25–p75 range, the heavy line the median, the whiskers reach p10–p90. $133k median in FY2025. Base pay only — hover a year for its figures.

$50k$100k$150k$200k$250k$300k’17’18’19’20’21’22’23’24’25’26

How has Karyopharm Therapeutics's H-1B hiring changed by year?

5 certified filings in FY2017 → 4 in FY2026. The change column is each year against the one before.

Karyopharm Therapeutics certified H-1B filings and base salary by fiscal year
Fiscal yearFilingsvs prior FYMedian base
FY20264−33%$189k
FY20256+500%$133k
FY20241−83%$125k
FY20236+20%$130k
FY20225+25%$150k
FY20214−50%$123k
FY20208+33%$110k
FY20196−40%$110k
FY201810+100%$110k
FY20175—$79k

Which wage levels does Karyopharm Therapeutics file?

DOL prevailing-wage levels I–IV approximate experience tiers (I = entry, IV = fully competent). 74% of Karyopharm Therapeutics's filings sit at Level III–IV. A heavy I–II skew reads as entry-level or contractor-style hiring; a heavy IV skew as senior in-house roles — and higher levels earn more lottery entries.

Share of 50 filings with a wage level · all years

20%
34%
40%
  • Level I6.0%3
  • Level II20.0%10
  • Level III34.0%17
  • Level IV40.0%20

What jobs does Karyopharm Therapeutics sponsor for H-1B?

The most-filed job titles across all years (DOL titles, employer pay-grade codes stripped), with base-salary percentiles.

Karyopharm Therapeutics most-sponsored H-1B job titles with base-salary percentiles
Job titleFilingsMedian base
Clinical Data Manager4$100k
Pharmacovigilance (Pv) Specialist4$110k
Senior Manager, Regulatory Operations4$170k
Senior Associate, Regulatory Operations3$130k
Senior Clinical Data Manager3$125k
Senior Biostatistician3$150k
Senior Medical Director, Pharmacovigilance3$265k
Sr Scientist, Analytical Chemistry2$144k
Senior Director, Regulatory Affairs2$220k
Pharmacovigilance Scientist2$110k

Where does Karyopharm Therapeutics hire H-1B workers?

Worksite states on the certified filings, all years. Deeper pink = more filings; hover a state for its figures.

146Certified filings (log scale)
Karyopharm Therapeutics H-1B worksite states
StateFilingsMedian base
MA46$120k
NC2$120k
AR2$125k
PA1$170k
NM1$101k
CA1$170k
VA1$133k
IL1$130k

What has Karyopharm Therapeutics filed recently?

The 50 most recent of 55 certified LCAs: job title, worksite, prevailing-wage level and the offered base salary.

Karyopharm Therapeutics recent certified H-1B LCA filings
FYJob titleBase salary
2026Associate Director, Regulatory Operations$188,500
2026Senior Manager, Regulatory Operations$190,215
2026Senior Manager, Regulatory Operations$188,500
2026Sr Scientist, Analytical Chemistry$153,480
2025Senior Clinical Data Manager$132,657
2025Manager, Regulatory Operations$139,932
2025Senior Statistical Programmer 1$123,966
2025Sr Clinical Data Manager$132,717
2025GCP Documentation Specialist$96,616
2025Senior Biostatistician$187,044
2024Senior Clinical Data Manager$124,500
2023Manager, Regulatory Operations$130,000
2023Sr Scientist, Analytical Chemistry$143,763
2023Manager Regulatory Operations$109,745
2023Senior Manager, Regulatory Operations$160,685
2023Senior Manager, Regulatory Operations$170,000
2023Senior Clinical Data Manager$120,000
2022Associate Director/Director, Clinical Pharmacology and Dmpk$170,475
2022GCP Documentation Specialist$86,781
2022Senior Medical Director, Pharmacovigilance$265,000
2022Senior Biostatistician$149,968
2022Clinical Data Manager$100,942
2021Associate Director/Director, Clinical Pharmacology and Dmpk$170,000
2021Senior Medical Director, Pharmacovigilance$265,000
2021Scientist, Analytical Chemistry$123,000
2021Clinical Data Manager$100,942
2020Principal Scientist$120,000
2020Senior Associate, Regulatory Operations$130,000
2020Associate Director, Xpovio U.s. Multiple Myeloma Marketing$165,000
2020Clinical Trial Manager$110,000
2020Regulatory Operations Associate$79,560
2020Senior Associate, Regulatory Operations$133,900
2020Clinical Data Manager$100,000
2020Clinical Data Manager$100,000
2019Senior Medical Director, Pharmacovigilance$265,000
2019Senior Biostatistician$140,000
2019Clinical Documentation Manager$100,000
2019Clinical Trial Associate$90,522
2019Senior Associate, Regulatory Operations$130,000
2019Pharmacovigilance Scientist$110,000
2018Pharmacovigilance Scientist$110,000
2018Senior Director, Regulatory Affairs$220,000
2018Senior Director, Regulatory Affairs$220,000
2018Associate Medical Director, Pharmacovigilance$200,000
2018Pharmacovigilance (Pv) Specialist$110,000
2018Pharmacovigilance (Pv) Specialist$110,000
2018Lead Clinical Research Associate$90,542
2018Pharmacovigilance (Pv) Specialist$110,000
2018Medical Director, Pharmacovigilance$260,000
2018Pharmacovigilance (Pv) Specialist$110,000

See all 55 filings →

Common questions about Karyopharm Therapeutics's H-1B filings

How much does Karyopharm Therapeutics pay H-1B workers?
Karyopharm Therapeutics's median certified H-1B base salary is $133k (FY2025), from 6 filings. See the full salary distribution and percentiles above.
How many H-1B workers does Karyopharm Therapeutics sponsor?
Karyopharm Therapeutics has 55 certified H-1B Labor Condition Applications on record (FY2017–FY2026).
What jobs does Karyopharm Therapeutics sponsor for H-1B?
Karyopharm Therapeutics's most-sponsored H-1B roles include Clinical Data Manager, Pharmacovigilance (Pv) Specialist, Senior Manager, Regulatory Operations, Senior Associate, Regulatory Operations.
Where does Karyopharm Therapeutics hire H-1B workers?
Karyopharm Therapeutics's top H-1B worksite states are MA, NC, AR, PA.
Does a certified LCA mean an H-1B visa was approved?
No. A Labor Condition Application (LCA) is the Department of Labor attestation an employer must have certified before filing an H-1B petition with USCIS. It records the job, worksite and offered wage, but not whether the petition was filed, selected in the lottery, or approved. Filing counts measure intent to sponsor, not headcount.
What salary do these figures show?
The base annual wage offered on the certified LCA, converted to a yearly amount. Bonus, equity, overtime and benefits are not included, so total compensation is typically higher. Figures are medians and percentiles over certified filings; wages above $5,000,000 a year are excluded as data-entry errors.
What do prevailing-wage levels I–IV mean?
The Department of Labor assigns each LCA an OES wage level from I (entry) to IV (fully competent) for the occupation and area. Under the FY2027 wage-weighted H-1B lottery rule, a higher level earns more selection entries, so an employer's level mix is a proxy for how senior its sponsored roles are.

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Source: U.S. Department of Labor, Office of Foreign Labor Certification — certified LCA disclosure data through June 2026 (FY2017–FY2026). An LCA is not an approved visa; pay figures are base salary and exclude bonus and equity. Methodology →